Survival and Recurrence in Non-melanoma Skin Cancers of scalp
محل انتشار: مجله تحقیقات سرطان، دوره: 2، شماره: 4
سال انتشار: 1397
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 262
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شناسه ملی سند علمی:
JR_MCIJO-2-4_003
تاریخ نمایه سازی: 28 بهمن 1399
چکیده مقاله:
Abstract
Introduction: Non-melanoma scalp skin cancers (NMSCs) including squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) are common. To manage such cancers, especially SCCs, more attention should be paid to their invasive characteristics. Mortality surveillance of SCCs and BCCs of scalp helps to choose proper approaches.
Methods: The current retrospective, descriptive study was conducted on 723 patients with NMSCs of scalp according to their epidemiologic and clinical manifestations. Invasive extended tumor (IET) are defined as aggressive SCCs and BCCs, which affect survival of patients. Therapies categorized in patients, and all the gathered data were analyzed.
Results: The 723 patients including 228 SCCs and 495 BCCs were evaluated in two compatible groups. Lymphatic metastasis, IET, and higher stages in SCCs were significant (P <0.005). Mean and 95% confidence intervals (CI) for SCCs and BCCs survival were 6.97 years (6.7-7.25) and 7.6 years (7.46-7.73), respectively, with significant difference between the groups (P=0.001); risk of mortality enhanced 2.05 and 22.07 times in SCC and IET clinical manifestation, respectively. Mean and 95% CI for recurrence time among SCCs and BCCs were 1.74 (1.26-1.75) and 2.26 (1.63-2.37) respectively, and there was a significant difference between the groups (P=0.001).
Conclusions: The current retrospective study showed that BCC frequency was twice more than that of SCC without significant dominancy on gender or age in scalp area with significant number of IET cases in SCCs. Mortality risks enhanced 2.05 times in SCCs and risk of recurrence increased 1.85 times in BCCs. These knowledge can guide to employ a proper approach.
کلیدواژه ها:
نویسندگان
Alireza Taheri
Tehran University of Medical Sciences
Alireza Khoshnevisan
associated professor of neurosurgery. Tehran University of Medical Sciences. Tehran, Iran
Abbas Alipour
assistant professor of epidemiology, Thalassemia research centre. Mazandaran University of Medical Sciences, Sari , Iran
Ghasemali Khorasani
Associated professor of plastic ;reconstructive surgery, medicine school, Tehran University of Medical Sciences, Tehran, Iran
Hojjat Molaei
Aassistant professor of plastic ;reconstructive surgery, medicine school, Tehran University of Medical Sciences, Tehran, Iran
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