ENZYBIOTICS ARE A GOOD ALTERNATIVE TOANTIBIOTICS

Background and Aim : Researchers have replaced traditional treatment approaches due to thespread of antibiotic resistance. Use of phages, or bacteria-contaminating particles, are antibacterialagents with a long-standing experience in some countries, currently employed to treat numerousinfectious disorders.Methods : The most recent information was gathered for this research using keywords, includingenzybiotics, antibiotics, bacteriophages, phage therapy, biological treatment, bacterial infection,and microbial resistance. The data were collected from databases such as Irandoc, Scopus,PubMed, and Google Scholar for the studies during ۲۰۱۸ and ۲۰۲۲.Results : Bacteriophages are viruses that can eradicate bacteria with little harm to the host cells.Therefore, They can be used either alone or in combination with antibiotics to treat bacterialinfections. Phage lysosomal enzymes can break down bacterial cell walls, which can be used todecelerate the spread of infectious agents. In this regard, the term "biotic enzyme," which refers toa large family of enzymes that can inhibit the growth of germs and functions similarly to someantibiotics, was developed. Moreover, bacteriophage resistance is easy to cure condition comparedto antibiotics. The adverse effects of this type of treatment are less severe than those of standardantibiotic therapy because the target cells (bacteria) and the invading agent (virus) have a veryspecific relationship to receptors that are not present in the host cells. The native flora, on the otherhand, is scarcely impacted by this treatment. To effectively eliminate bacteria that create toxins,new viral strains are now being designed that kill bacteria rather than lyse them. Therefore, it isevident that enzybiotics are a viable choice for infection treatment.Conclusion : The results of the studies show that enzybiotics are effective in the treatment ofinfection, and the use of phages as new drugs in limiting the growth of infectious bacteria is ofhigh priority and importance and needs to be fully considered.

کلیدواژه ها:

Bacteriophage ، Phage Therapy ، Microbial Resistance ، Antibiotic ، Enzybiotics